Quality Digest recently featured Inorganic Ventures in the article, “Beyond the Pit: Why Laboratory Integrity Now Shapes Mining Viability,” highlighting the growing role analytical accuracy plays in the future of mining operations.
The article examines how mining companies are operating under increasingly narrow economic margins as lower-grade deposits and complex rare earth materials become more common. In these environments, analytical data is no longer just a supporting fun
Global Mining Review recently featured Inorganic Ventures in the article, “Beyond the Pit: Why Laboratory Integrity Now Shapes Mining Viability,” highlighting the growing importance of analytical precision in modern mining operations. (
We’re excited to share that Inorganic Ventures was recently referenced in a Labcompare article exploring the growing importance of laboratory integrity in the mining industry.
When performing elemental analysis most sample preparation and data workup is done in units of µg/g, µg/mL, µg/L, etc. However, when working with pharmaceutical samples the Permitted Daily Exposure (PDE) limits are reported in units of µg/day. Since different pharmaceutical products have different maximum dosages, it is critical to convert the conventional units used by elemental analysts into something that can be equated back to the PDE limit unit of µg/day. The J Value is used to perform this conversion.
If you are testing pharmaceutical samples using USP <232> / <233> and/or ICH Q3D, then you may be familiar with the concept of the J value. The J value is defined below:
PDE limits are determined by USP <232> and ICH Q3D, but the dilution factor and maximum daily dose is determined by you and your sample. The reason that the PDE limit is converted to a J
Poor sample washout or carryover effects can be the cause of inaccurate results when using ICP analysis techniques. Ideally the instrument signal should return to background levels between analyzing samples and standards. Samples
EPA Method 200.8 is an established and widely used ICP-MS method. It describes the analysis of water and wastes for 21 elements. Included in these 21 elements is arsenic, which has a large potential polyatomic interference from 40Ar35Cl. It is common for analysts to face a high bias in their data for 75As. To correct for this potential 40Ar35Cl interference EPA Method 200.8, Table 5, prescribes using the correction equation below:
This correction equation subtracts the counts of 40Ar35Cl from the total counts recorded for mass 75. This is done by measuring the counts from a similar polyatomic: 40Ar37Cl. In theory, the counts for 40Ar35Cl and 40Ar37Cl should be the same
We’re proud to announce a major milestone in the continued integration of PURE Analytical Laboratories into the IV Labs family: Will Marble has been named President of PURE, effective July 1, 2025.
Will is a long-time executive at IV Labs and a New River Valley resident with over 14 years of leadership across operations, supply chain, and commercial strategy. His appointment reflects IV Labs’ commitment to developing leaders from within and further aligning PURE’s capabilities with our Virginia-based operations.
PURE Analytical Laboratories, based in Feasterville, Pennsylvania, joined the IV Labs portfolio in July 2024. Since then, the PURE team has continued to serve customers around the globe with ultr
NIST-traceable standards are reference materials certified to specific values laid out by the National Institute of Standards and Technology (NIST). They are designed specifically for standardized instrument calibration and quality assurance protocols aimed at eliminating measurement uncertainties. The implication with NIST-traceable standards is that all calibrations are part of an unbroken chain of comparisons from the manufacturer through to the end-user, which is where the term traceability comes from.
Traceability is a crucial parameter in elemental analysis and wet chemistry applications. When we talk about the traceability of measurements, we are referring to systemic reliability – and subsequently the reliability of your results – relative to an accepted set of standards. This is the basic premise of standardized metrology and the international system of units (SI). Yet the traceability of chemical measurements is
References are a key part of analytical testing. Choosing the right type of reference for your testing procedure is an essential part of process design and achieving the right levels of quality management.
In analytical testing, reference materials are used for calibration, quantification and verification. Using a material with known properties makes it possible to deconvolute the response of the analyte from the response of the instrument. In turn, this results in more accurate measurements of concentration, as well as qualitative measures such as the positions of spectral features for spectroscopic measurements or retention times in chromatography.1
Inorganic
Certified reference materials (CRMs) ensure accuracy and reliability in analytical workflows–but only if they are accurate and reliable themselves. A certificate of analysis (CoA) affirms the integrity of CRMs to reinforce the unbroken chain of traceability.
A CoA for CRMs provides comprehensive details about the material’s composition, purity, and traceability. It lists certified values for specific analytes, outlines measurement uncertainties, describes the analytical methods employed, and ensures traceability to national or international standards. By verifying that the CRM meets rigorous quality criteria, the CoA supports reliable calibration, method validation, and quality control in analytical laboratories. This document is key to ensuring the accuracy and dependability of results derived from the CRM.
