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Chemical Stability and Compatibility - Transpiration in polycarbonate vs. polypropylene sample tubes

 
I found the updated transpiration guide very useful. I am wondering if you have any studies or info on the transpiration of polycarbonate versus polypropylene? My issue is I have a sample submitter that switched from using 15 mL polypropylene centrifuge tubes for biological sample digests containing ~20% (vol/vol) nitric acid to polycarbonate 15 mL vials. In one sample batch submitted to me the final volume (which was supposed to be 10 mL) they mixed the tubes and the polycarbonate vials are at a final volume of ~8.5 - 9.0 mL while the polypropylene vials are at ~ 10 mL - this is after ~8 months of storage at room temperature and the tops wrapped with parafilm (despite my recommendation not to do this). This seems to be a lot of volume loss, assuming the volume markings on the tubes are somewhat accurate which I am checking into. Thanks for any info!
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We have not studied transpiration rates for polycarbonate containers, and do not know how this material would compare to polypropylene. There is a fair amount of literature available from the packaging industry, where transpiration is frequently characterized as water vapor transmission rates (WVTR). Considering the size and geometry of the tubes our first thoughts were that the cap design and quality of the seal would be the most important factors. However, a quick internet search on the term “polycarbonate water vapor transmission rate” resulted in a physical properties table published by ThermoScientific that lists WVTR for different plastics. These data suggest that polycarbonate has a WVTR approximately 30 times greater than that of polypropylene, and this may offer a better explanation for your observations.

Posted: 09/02/18 22:38:58

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