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General Spectroscopy - Trace metal impurity data

 
I have some questions about trace impurities reported on the certificate of analysis for 1000 ug/mL and 10 000 ug/mL Al solutions. The impurity values are reported with 4 to 6 significant figures for most analytes – how do you get such accurate values? Are the less than (<) values IDL, MDL or RL – how to assign the same or different impurity values for 1000ug/mL and 10000ug/mL Al solutions, respectively, that are directly reported from analytical results (with/without correction), scientific judgment or computer generated? Calibration standards and their concentration used for impurity analysis? How long to complete impurity analysis and report of each product.
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admin Total posts: 529

The answers to your questions are below, and in the order in which they were asked.

  1. This is a result of our software system.  The DL is only accurate to one significant figure.
  2. They are generated by the analyst and are a function of the spectra – rarely do we get DLs that are as low as IDLs.
  3. Concentrations vary from 4 ppb to 1 ppm and the techniques used are calibration curve for OES and standard additions for MS.
  4. It takes about 1 day/ product because data are gathered by both OES and MS and then the data and spectra are interpreted by a trace analyst.  Some simple spectral systems are quicker and the more complex spectral chemical systems can take longer.
Posted: 09/04/18 20:37:27

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