General Spectroscopy - Measuring lithium (Li) using Li isotopes
Can you tell me if you can analyze for Lithium in samples by analyzing for Lithium 7 while using Lithium 6 in an internal standard mix?
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admin
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The procedure you’re describing is isotope dilution mass spectrometry, where very accurate and precise concentrations can be determined. The basic premise is that you will know: 1) the concentration of the Li-6 internal standard that you spike into your sample, 2) the isotopic ratio of Li in the Li-6 internal standard, and 3) the isotopic ratio of Li in your sample, which you would assume to be natural (unless you have reason to believe otherwise). Armed with these pieces of information you measure the Li isotopic ratio in your spiked sample, and from that you can calculate the Li concentration in the sample. Wikipedia offers a nice synopsis describing the technique:https://en.wikipedia.org/wiki/Isotope_dilution. |